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The following projects are currently open and enrolling volunteers. These studies were evaluated and approved by the research team at Dr. Susan Love Research Foundation and members of our external Scientific Advisory Committee, comprised of researchers, clinicians, and advocates.
If you would like to learn about the studies we recruited for in the past, please click here.
A research team at Johns Hopkins wants to learn how to improve access to follow-up care for women who get an abnormal breast cancer screening result. To learn what care women do or don’t get, the research team is having about 500 women who received abnormal results from a mammogram, breast MRI, or clinical breast exam or a diagnosis of breast cancer complete a 30-minute survey about their healthcare experiences.
The research team recruited for this study in July 2018 and enrolled more than 200 women. Most of the women who signed up to participate were White and heterosexual. To better assess healthcare experiences across populations, the research team is now looking for participants from other racial / ethnic groups and sexual orientations.
All breast cancer patients have many decisions to make as they decide which breast cancer surgery, and other treatments, are right for them. These decisions may be influenced by input from family, friends, and doctors – but what is important to them might not be what matters most to the patients themselves. The purpose of this study is to better understand which factors women and men find most important as they consider different surgical treatment options. The researchers completed enrollment of participants without a breast cancer diagnosis and now need women who had a single or double mastectomy after a breast cancer diagnosis. The researchers will use what they learn to improve how health care providers approach shared decision-making with their breast cancer patients.
Some people live for many years following a metastatic breast cancer diagnosis. To gain insight into why, researchers want to learn more about the medical history and health habits of women and men living with metastatic breast cancer. If you take part in this study, you will complete an online survey that will ask you questions about diet, exercise, health behaviors and medical care. Some participants who fill out the survey will also be invited to participate in an optional sub-study, which includes a medical record review, a blood or saliva sample, and tumor analysis. Findings from the survey and optional sub-study may help the research team discover how to help people live longer after a diagnosis of metastatic breast cancer.
Women and men with hormone receptor-positive (ER+ and/or PR+) breast cancer may receive several different treatments to stop or slow the cancer’s growth. Over time, cancer cells can stop responding to these treatments, which can lead to local or distant metastases.
A research team is trying to find ways to keep hormone-resistant tumors responding to hormone therapies for longer periods of time. This phase III clinical trial aims to confirm what was found in a previous trial: that patients who received a standard hormonal treatment, exemestane (Aromasin), together with an investigational drug called entinostat, lived longer without the breast cancer growing or spreading, versus exemestane (Aromasin) alone. Researchers hope to verify these findings in this larger study. This trial, if positive, could potentially lead to a new FDA-approved treatment option that may help some patients live longer, experience symptom relief, or improve their quality of life.
The purpose of this study is to compare the effects of tamoxifen pills to tamoxifen (4-OHT) gel on breast cells in women with ER+ DCIS. This study will investigate what effects each treatment has on the DCIS and what side effects each treatment may cause. The eventual goal is to provide women with DCIS with an alternative to oral tamoxifen.
Women receive mixed messages about what type of breast cancer screening they should have and how often they should have mammograms. The WISDOM Study compares the routine, annual mammogram schedule to a personalized screening schedule based on a woman’s individual risk factors. The goal of the study is to determine the best way to use mammograms to improve breast cancer screening while reducing the number of call backs, false alarms, and biopsies for women who do not have breast cancer.
The purpose of this study is to learn about the best ways to improve access to breast cancer care and treatment for members of the Black LGBQ-SGL community. The research team will enroll up to 30 participants for an in-depth phone interview about identities and healthcare experiences.
The purpose of this study is to test the effects of three physical activity programs among women with stage 0 to stage 3 breast cancer. This is a randomized controlled trial, therefore the research team is interested to see which program(s) help participants increase and maintain their level of physical activity. Survivors’ mood, fatigue, and quality of life will also be examined over the one-year duration.
The purpose of this study is to better understand why some breast cancer survivors who have chronic pain and are treated with duloxetine will have their level of pain improve, while others will not. Women with breast cancer who have chronic pain will be asked to enroll. Participants will be treated with duloxetine for 7 weeks in order to determine how the medication affects both their level of pain and their sensitivity to pain. The research team hopes to understand more about why breast cancer survivors develop pain after their diagnosis and treatment, and why some people respond better to this type of treatment. The research team needs 56 women to participate in this study.
The purpose of this study is to learn more about what breast cancer survivors age 65 and older know about the physical and functional impairments related to their breast cancer and its treatment. It will also help the research team understand what can be done to help people recover from breast cancer. This study is seeking 50 breast cancer survivors and 50 healthcare providers for a one-time, one-hour phone interview.