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Current Projects

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The following projects are currently open and enrolling volunteers. These studies were evaluated and approved by the research team at Dr. Susan Love Research Foundation and members of our external Scientific Advisory Committee, comprised of researchers, clinicians, and advocates.

If you would like to learn about the studies we recruited for in the past, please click here.

Researcher: Hinaben Panchal, MD, MPH, and Evan Matros, MD, MMSc, MPH at Memorial Sloan Kettering Cancer Center, New York, NY
Broadcast date: June 22, 2018

The research team at Memorial Sloan Kettering Cancer Center in New York City created a questionnaire that simulates a decision-making process for breast cancer surgery. If you are eligible for this study, you will receive a link to the online questionnaire. You will be asked to answer situational questions, where you learn about and choose between different treatment options. If you have been diagnosed with breast cancer, you will also be asked about your breast cancer, surgery, and how cancer has personally affected you.

Participants are not required to provide any identifying information. The questionnaire should take approximately 10 minutes to complete. You can take breaks while answering the questions and return to where you left off, as long as you use the same computer.

Researcher: Mark Burkard, MD, PhD, University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Broadcast date: May 10, 2018

Some people live for many years following a metastatic breast cancer diagnosis. To gain insight into why, researchers want to learn more about the medical history and health habits of women and men living with metastatic breast cancer. If you take part in this study, you will complete an online survey that will ask you questions about diet, exercise, health behaviors and medical care. Some participants who fill out the survey will also be invited to participate in an optional sub-study, which includes a medical record review, a blood or saliva sample, and tumor analysis. Findings from the survey and optional sub-study may help the research team discover how to help people live longer after a diagnosis of metastatic breast cancer.

Researcher: Susan Love, MD, MBA, Dr. Susan Love Research Foundation, Encino, CA
Broadcast date: May 4, 2018

The purpose of this research study is to create a functional map of the breast ducts so that doctors can better diagnose, treat, and – eventually – learn how to prevent breast cancer.  The research team will first determine the ideal state of the lactating breast for imaging, i.e. full, empty, or in between, as well as the best procedure for capturing the data. The second step will involve recruiting 250 women who are breast feeding to take part in this low risk investigation and undergo whole breast Automated Whole Breast Ultrasound. The research team is currently recruiting 50 women to participate in the first step of this study.

Researcher: Gwendolyn Thomas, PhD, Syracuse University, Syracuse, NY
Broadcast date: April 30, 2018

Studies have found that exercise can reduce the risk of a breast cancer recurrence. Exercise also improves quality of life. Many breast cancer survivors understand these benefits, but find it challenging to get started. In collaboration with breast cancer survivors, a research team at Syracuse University has developed an app to help survivors exercise whenever it is easiest for them.

The purpose of this study is to investigate whether an exercise app can help breast cancer survivors increase their physical activity level. The app can be accessed via an Apple or Android smartphone or tablet. Participation includes daily instruction via the app, guidance on aerobic and resistance exercises, activity monitoring with a physical activity tracker, and surveys throughout the seven weeks.

Researcher: Roisin M. Connolly, M.B., B.Ch., Lead investigator for E2112 Study. Assistant Professor of Oncology, Johns Hopkins University, Baltimore, MD
Broadcast date: April 19, 2018

Women and men with hormone receptor-positive (ER+ and/or PR+) breast cancer may receive several different treatments to stop or slow the cancer’s growth. Over time, cancer cells can stop responding to these treatments, which can lead to local or distant metastases.

A research team is trying to find ways to keep hormone-resistant tumors responding to hormone therapies for longer periods of time. This phase III clinical trial aims to confirm what was found in a previous trial: that patients who received a standard hormonal treatment, exemestane (Aromasin), together with an investigational drug called entinostat, lived longer without the breast cancer growing or spreading, versus exemestane (Aromasin) alone. Researchers hope to verify these findings in this larger study. This trial, if positive, could potentially lead to a new FDA-approved treatment option that may help some patients live longer, experience symptom relief, or improve their quality of life.  

View the ECOG-ACRIN video for this study

Researcher: Seema Khan, MD, Northwestern University, Chicago, IL, Joseph Michael Guenther, MD, St. Elizabeth HealthCare, Edgewood, KY, Amy Degnim, MD, Mayo Clinic, Rochester, MN, Melissa Pilewskie, MD, Memorial Sloan Kettering Cancer Center, New York, NY, E. Shelley Hwang, MD, Duke University, Durham, NC, Stephen Grobmyer, MD, Cleveland Clinic, Cleveland, OH
Broadcast date: February 16, 2018

The purpose of this study is to compare the effects of tamoxifen pills to tamoxifen (4-OHT) gel on breast cells in women with ER+ DCIS. This study will investigate what effects each treatment has on the DCIS and what side effects each treatment may cause. The eventual goal is to provide women with DCIS with an alternative to oral tamoxifen.

Researcher: Laura Esserman, MD, MBA, University of California, San Francisco, CA and her partners from the Athena Breast Health Network (a collaboration across the five University of California Medical Centers and Sanford Health)
Broadcast date: February 16, 2018

Women receive mixed messages about what type of breast cancer screening they should have and how often they should have mammograms. The WISDOM Study compares the routine, annual mammogram schedule to a personalized screening schedule based on a woman’s individual risk factors. The goal of the study is to determine the best way to use mammograms to improve breast cancer screening while reducing the number of call backs, false alarms, and biopsies for women who do not have breast cancer.

Researcher: Tonia Poteat, PhD, and Lorraine T. Dean, ScD of Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Broadcast date: January 17, 2018

The purpose of this study is to learn about the best ways to improve access to breast cancer care and treatment for members of the Black LGBQ-SGL community. The research team will enroll up to 30 participants for an in-depth phone interview about identities and healthcare experiences.  

Researcher: Bernardine Pinto, Ph.D., Professor and Associate Dean of Research in the College of Nursing at the University of South Carolina, Columbia
Broadcast date: October 18, 2017

The purpose of this study is to test the effects of three physical activity programs among women with stage 0 to stage 3 breast cancer. This is a randomized controlled trial, therefore the research team is interested to see which program(s) help participants increase and maintain their level of physical activity. Survivors’ mood, fatigue, and quality of life will also be examined over the one-year duration.

Researcher: N. Lynn Henry, MD, PhD; Anna Beck, MD; Adam Cohen, MD; Saundra Buys, MD; John Ward, MD; Hung Khong, MD; Elizabeth Prystas, MD
Broadcast date: October 3, 2017

The purpose of this study is to better understand why some breast cancer survivors who have chronic pain and are treated with duloxetine will have their level of pain improve, while others will not. Women with breast cancer who have chronic pain will be asked to enroll. Participants will be treated with duloxetine for 7 weeks in order to determine how the medication affects both their level of pain and their sensitivity to pain. The research team hopes to understand more about why breast cancer survivors develop pain after their diagnosis and treatment, and why some people respond better to this type of treatment. The research team needs 56 women to participate in this study.